Journal article
Multidomain Modifiable Dementia Risk Factors Are Associated With Poorer Cognition in Midlife
L Bransby, E Rosenich, RF Buckley, N Yassi, MP Pase, P Maruff, YY Lim
Neuropsychology | AMER PSYCHOLOGICAL ASSOC | Published : 2023
DOI: 10.1037/neu0000900
Abstract
Objective: Studies of modifiable dementia risk factors (MDRFs) generally consider MDRFs individually, despite strong evidence that they co-occur in adult populations. In a large sample of middle-aged adults, this study aimed to determine the frequency and co-occurrence of MDRFs, spanning five domains (mood symptomatology, risky lifestyle behaviors, cardiovascular conditions, cognitive/social engagement, sleep disorders/symptomatology). The relationship between number of domains in which MDRFs were reported with cognitive performance and subjective cognitive concerns was then determined. Method: Middle-aged adults (n=1,610) enrolled in the Healthy Brain Project and completed self-report surve..
View full abstractGrants
Awarded by National Institutes of Health
Funding Acknowledgements
The Healthy Brain Project (https://healthybrainproject.org.au) is funded by the National Health and Medical Research Council (GNT1158384, GNT1147465, GNT1111603, GNT1105576, GNT1104273, GNT1158384, GNT1171816), the Alzheimer's Association (AARG-17-591424, AARG-18-591358, AARG-19643133), the Dementia Australia Research Foundation, the Bethlehem Griffiths Research Foundation, the Yulgilbar Alzheimer's Research Program, the National Heart Foundation of Australia (102052), and the Charleston Conference for Alzheimer's Disease. The authors thank their study partners (PearlArc, SRC Innovations, Cogstate Ltd., and Cambridge Cognition) for their ongoing support.